BONE GRAFTS
What are bone grafts? Bone grafts are the materials used for replacement or augmentation of the bone. · Enhances regenerative capacity of bone · Achieve new attachment apparatus Biologic concept of using bone graft: 1. Osteoconduction 2. Osteoinduction 3. Osteogenesis OSTEOCONDUCTION (Trelli’s effect): “ Physical effect” by which the matrix of the graft forms a scaffold that favors outside cells to penetrate the graft and form new bone . E.g: Alloplast, FDBA OSTEOINDUCTION: Chemical process by which molecules contained in the graft (e.g., bone morphogenetic proteins) convert the neighboring cells into osteoblasts, which in turn form bone . E.g: DFDBA OSTEOGENESIS: Osteoblasts in the transplanted bone having adequate blood supply & cellular viability forms new centers of ossification within the graft. E.g: Autogenous graft INDICATIONS FOR GRAFTS 1. Deep Intraosseous Defects 2. Tooth Retent